aldose reductase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14175	Aldose reductase-IN-1	AT-001,Caficrestat	Others , Reductase
	Aldose reductase-IN-1 (AT-001) is a aldose reductase inhibitor (IC50: 28.9 pM).		Others , Reductase
T16910	Sorbinil		Reductase
	Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit the polyol pathway.		Reductase
T22757	EBPC		Reductase
	EBPC is an inhibitor of aldose reductase.		Reductase
T6S2384	Poliumoside		Reductase
	Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhibits great inhibitory effects on rat lens aldose reductase w...		Reductase
T23403	Sulindac sulfone		Reductase , COX
	Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac.		Reductase , COX
T10393	AT-007		Reductase
	AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prevents disease complications in GALT deficiency rats.		Reductase
T2013	Ponalrestat		Reductase
	Ponalrestat is an aldose reductase inhibitor.		Reductase
T35317	Zopolrestat	CP 73850,CP73850,CP-73850,Zopolrestatum	Reductase
	Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).		Reductase
T17114	Tolrestat	AY-27773	Reductase
	Tolrestat (AY-27773) is a potent inhibitor of aldose reductase (IC50 = 35 nM).		Reductase
T62951	Aldose reductase-IN-2
	Aldose reductase-IN-2 (Compound 5f) is a potent inhibitor of aldose reductase (AR) with antioxidant properties. aldose reductase-IN-2 is a promising anti-diabetic complication drug.
T5S1131	Ganoderic acid C6		Others
	1. Ganoderic acid C6 has antinociceptive activity.		Others
T61555	Aldose reductase-IN-6
	Aldose reductase-IN-6 (Compound 3) is a competitive inhibitor of aldose reductase (AR), possessing an IC50 of 3.164 μM and a Ki of 0.018 μM. Notably, Aldose reductase-IN-6 demonstrates no cytotoxicity toward normal cells...
T60897	Aldose reductase-IN-5
	Aldose reductase-IN-5 is an inhibitor of aldose reductase (ALR2) that enhances the combination of inhibitory excitability and antioxidant capacity, thereby delaying the diabetes complications progress.
T61957	Aldose reductase-IN-3
	Aldose reductase-IN-3 (Compound 5) is an effective and moderately selective aldose reductase (AR) inhibitor (IC50=3.99 μ M). Aldose reductase is a molecular target involved in various inflammatory diseases (including sep...
T60601	Aldose reductase-IN-4
	Aldose reductase-IN-4 (compund IIc) is an inhibitor of aldose reductase with IC50s of 11.70 μM and 0.98 μM for ALR1 and ALR2, respectively [1].
T5195	Alrestatin	AY-22284	Reductase
	Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.		Reductase
T1458	Epalrestat	ONO2235	Reductase
	Epalrestat (ONO2235), an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy and delay the progression of the disease, particul...		Reductase
T0725	Isoliquiritigenin	ISL,Isoliquiritigen,GU17	Apoptosis , Influenza Virus , Reductase , Autophagy
	Isoliquiritigenin (ISL), an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).		Apoptosis , Influenza Virus , Reductase , Autophagy
T15568	Imirestat	Alcon 1576,AL 1576,HOE 843	Reductase
	Imirestat (HOE 843) is an aldose reductase inhibitor that can be used in diabetes research.		Reductase
T3801	(Rac)-Byakangelicin	Bjacangelicin,Bjakangelicin,Biacangelicin,7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-,Byakangelicin	Others
	(Rac)-Byakangelicin (7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-) is an antineoplastic agent.		Others